Auto-injectors for intramuscular and subcutaneous <br>administration.
Auto-injectors for intramuscular and subcutaneous administration.
Aidaptus
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Weitere Informationen über unsere Autoinjektor-Technologien
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Auto-injector Technology |
Description |
Benefit |
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Drug Delivery - Spring type and position |
Compression Spring |
Positioned rearward to the syringe |
Common simple standard approach for auto-injectors |
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External compression spring outside the syringe |
Spring is positioned outside the syringe creating a larger diameter device and providing flexibility in the delivery force |
Allows administration of higher viscosity drugs Suitable for variable doses associated with some therapies |
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Internal Compression Spring |
Spring is positioned inside the syringe |
Reduces the size of the auto-injector enabling a compact size Providing a discreet device for the patient |
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Constant Force Spring |
Adds flexibility in the delivery force curve |
Helps with reusable devices especially for viscous drug |
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Auto-injector Technology |
Description |
Benefit |
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Needle protection and needlestick prevention |
Needle Retraction |
Needle is retracted rearwards into the device body which could include a dampening mechanism accommodating syringes with large tolerances |
Provides needle protection with needle hidden before, during and after use helping patients with needle fear & phobias |
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Needle Shroud |
Needle shroud moves forward to fully encase needle |
Provides needle protection with needle hidden before, during and after use helping patients with needle fear & phobia. The design reduces complexity with a lower component count compared to devices with retracting designs |
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Auto-injector Technology |
Description |
Benefit |
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Pre-activation safety features |
Pre-activation safety interlock on device |
Interlock design requires the user to push the device onto the skin, engaging the front and back body which releases the safety interlock mechanism |
Provides safer patient control preventing accidental firing/activation of the device before use |
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Interlock Cap |
Cap is securely locked onto device |
Protects the device before use |
| Auto-injector Technology | Description | Benefit | |
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| Activation mode | Button Activated - side fire | Device activated with a button on side on the auto-injector | Button activation may provide patient with additional control of their drug administration |
| Button Activated - top fire | Device activated with a button on the top of the auto-injector | Button activation may provide patient with additional control of their drug administration | |
| Automatic Contact Activated | Needle is automatically inserted once the patient depresses the auto-injector in the injection site |
Auto-injector has fewer components than button activated devices Patient has fewer user steps reducing complexity & providing ease of use |
| Auto-injector Technology | Description | Benefit | |
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Needle Insertion |
Automatic needle insertion in separate phases |
Needle is automatically inserted into the skin Independent 2 phase needle insertion and drug delivery with one spring for needle insertion and then a second spring for drug delivery |
Consistency of injection experience for patient. Ensures the needle is fully inserted into the skin before the drug starts to be delivered which may help to reduce wet injections |
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Automatic needle insertion during the delivery phase |
Automatic needle insertion in a single phase, which also continues to provide drug delivery |
Consistency of injection experience for patient |
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Manual |
Patient controls needle insertion manually |
Simple mechanism with less components & reduced complexity |
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Auto-injector Technology |
Description |
Benefit |
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Arming the auto-injector |
Manual |
User uses the device to push and arm the spring, before injection |
Complete patient control |
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Pre-armed |
No arming required |
No action required by patient device before use |
| Auto-injector Technology | Description | Benefit | |
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| Dosing | Variable Dose | Auto-injector with single use pre-filled syringe allows the user to select different doses of drug in the same device, according to their drug treatment regime | Reduces the number of SKUs for multiple drug doses |
| Multiple Dose | Auto-injector with multiple use cartridge allows the user to select variable doses of drug in the same device, according to their drug & treatment regime | Provides dose flexibility in a single device | |
| Fixed Dose |
Auto-injector with single use pre-filled syringe for a defined fill volume. |
Simple and intuitive to use with minimal user steps. No dosage errors |
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Auto-injector Technology |
Description |
Benefit |
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Type of Device |
Re-usable |
Auto-injector can be used repeatedly with multiple primary containers: pre-filled syringe or cartridge |
Sustainability benefits from the reuse of the device for potentially years |
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Single-use |
Auto-injector can be used just once before disposal |
Simple to use with less user steps than a re-usable device Provides patient convenience Typically smaller than reusable devices |
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Auto-injector Technology |
Description |
Benefit |
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Additional Features |
Fill volume flexibility |
Self-adjusting plunger accommodates different fill volumes in the same device |
Provide pharmaceutical manufacturers the option to modify drug volumes without needing to change their selected delivery device. Provides flexibility for formulation changes in drug development, clinical trials and life cycle management |
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Integrated Container Closure Integrity |
Plunger rod is positioned to prevent rearward movement of the stopper into an area with potentially compromised sterility |
Maintains sterility of the primary container contents by ensuring that the stopper cannot move into an unsterile area of the syringe during transport and storage |
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| Customised overwrap | Printable wrap covering the outside of the device | Rapid customisation can be achieved including colour, branding and window sizes |
Auto-injecteurs conçus pour une gamme de traitements destinés à l’auto-administration par le patient
Notre gamme de dispositifs auto-injecteurs avancés est compatible avec l’auto-injection par le patient ; elle a été conçue pour rendre l’expérience d’injection simple, pratique et plus facile à gérer. Ils peuvent être utilisés pour administrer différents médicaments nécessitant une seringue. Notre plateforme Autoject® 2 a joué un rôle clé dans ce domaine et a été utilisée pour l’administration de nombreux traitement, notamment pour la polyarthrite rhumatoïde, la sclérose en plaques, le déficit en hormone de croissance et l’anaphylaxie. En fabriquant constamment des appareils de haute qualité, nous avons acquis une réputation de confiance auprès de nos utilisateurs finaux et de nos partenaires.
